This recent study from Japan (Yabe, Higo, Sugita & Hiwamori, European Archives of Oto-Rhino-Laryngology March, 2008, 265(3): 1434-4726 ) compared middle ear effusion (MEE) proteins with serum proteins using gel chromatography and observed that IgA and IgG but not IgM are present in higher concentration in MEE than sera
This open access paper from UK (T. Upile et al, BMC Ear, Nose and Throat Disorders 2007, 7:4doi:10.1186/1472-6815-7-4) examined the issue of alcohol consumption on hearing threshold and reported positive association between increasing breath alcohol concentration and magnitude of increase in hearing threshold foor most hearing frequencies
february 14 2008
Vol 7, No 9
Otorhinolaryngology news
· MEE Proteins Xteristics…?
· Alcohol & Auditory threshold…?
· Fluid + Pressure & ME Function..?
· Case of The week
Journal Watch: Is External Noise a Risk to Fetal Hearing Development? A Review, F.E. Thurston, 2008
1. Home page of otolaryngologyinafrica.net re-designed for accessibility
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4. Papers delivered at the 16th ORLSON Scientific Meeting held November 21—24, 2007 can be viewed HERE
5. Forum topic : Case of the Week—Vol7,No4. Read the preview HERE
6. Blog Topic: OSAS
Till Next Week,
Biodun
The effect of fluid on middle ear (ME) dynamics is well known. So also is the effect of negative ME pressure. This study examined the combined effect of fluid and pressure on ME function using fresh frozen human cadaveric temporal bone and observed that TM movement reduction caused by combine fluid + pressure was not synergistic but higher than that by middle ear fluid alone, but less than that by middle ear pressure alone
ABSTRACT:
In our previous studies, the effects of effusion and pressure on sound transmission were investigated separately. The aim of this study is to investigate the combined effect of fluid and pressure on middle ear function. An otitis media with effusion model was created by injecting saline solution and air pressure simultaneously into the middle ear of human temporal bones. Tympanic membrane displacement in response to 90 dB SPL sound input was measured by a laser vibrometer and the compliance of the middle ear was measured by a tympanometer. The movement of the tympanic membrane at the umbo was reduced up to 17 dB by the combination of fluid and pressure in the middle ear over the auditory frequency range. The fluid and pressure effects on the umbo movement in the fluid–pressure combination are not additive. The combined effect of fluid and pressure on the umbo movement is different compared with that of only fluid or pressure change in the middle ear. Negative pressure in fluid–pressure combination had more effect on middle ear function than positive pressure. Tympanometry can detect the middle ear pressure of the fluid–pressure combination. This study provides quantitative information for analysis of the combined effect of fluid and pressure on tympanic membrane movement.
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Abstract: Background: There is very little knowledge about alcohol-induced hearing loss. Alcohol consumption and tolerance to loud noise is a well observed phenomenon as seen in the Western world where parties get noisier by the hour as the evening matures. This leads to increase in the referrals to the "hearing aid clinic" and the diagnosis of "cocktail party deafness" which may not necessarily be only due to presbyacusis or noise-induced hearing loss. Methods: 30 healthy volunteers were recruited for this trial which took place in a controlled acoustic environment. Each of the individuals was required to consume a pre-set amount of alcohol and the hearing was tested (using full pure tone audiogram) pre- and post- alcohol consumption over a broad range of 6 frequencies. Volunteers who achieve a minimum breath alcohol threshold level of 30 u/l had to have second audiogram testing. All the volunteers underwent timed psychometric and visuo-spatial skills tests to detect the effect of alcohol on the decision-making and psychomotor co-ordination. Results: Our results showed that there was a positive association between increasing breath alcohol concentration and the magnitude of the increase in hearing threshold for most hearing frequencies. This was calculated by using the Pearson Regression Coefficient Ratio which was up to 0.6 for hearing at 1000 Hz. Over 90% of subjects had raised auditory thresholds in three or more frequencies; this was more marked in the lower frequencies.
Conclusion: Alcohol specifically blunts lower frequencies affecting the mostly 1000 Hz, which is the most crucial frequency for speech discrimination. In conclusion alcohol does appear to affect auditory thresholds with some frequencies being more affected than others.
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This 31 year old male presented with 5/12 history of hoarseness and productive cough. He also gave past history of recurrent neck discharge from ’boils’ following previous antibiotic Rx. Neck examination reveal the following >>>
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